Mupirocin resistance related to increasing mupirocin use in clinical isolates of methicillin-resistant Staphylococcus aureus in a pediatric population.
نویسندگان
چکیده
We investigated the proportion of methicillin-resistant Staphylococcus aureus (MRSA) isolates from pediatric patients demonstrating mupirocin resistance related to mupirocin use at our institution. No mupirocin resistance was found in 98% of isolates, whereas mupirocin prescriptions increased by 110%. Resistance rates remained low despite the increasing use of mupirocin.
منابع مشابه
Emergence of Mupirocin Resistance among Clinical Isolates of Methicillin Resistant Staphylococcus Aureus –– a Challenging Threat to Hospital Care in a Rural Medical College of Eastern India
Mupirocin is a topical antimicrobial agent utilized in treatment of methicillin resistant Staphylococcus aureus. Mupirocin resistance in Staphylococcus aureus is increasingly being reported in many parts of the world in the context of its widespread use. The objectives of this study were to determine the susceptibility of methicillin resistant Staphylococcus aureus clinical isolates to mupiroci...
متن کاملHigh prevalence of mupirocin resistance in Staphylococcus aureus isolates from a pediatric population.
Topical mupirocin is used widely to treat skin and soft tissue infections and to eradicate nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA). Few studies to date have characterized the rates of S. aureus mupirocin resistance in pediatric populations. We retrospectively studied 358 unique S. aureus isolates obtained from 249 children seen in a predominantly outpatient setting ...
متن کاملThe Prevalence, Genotype and Antimicrobial Susceptibility of High- and Low-Level Mupirocin Resistant Methicillin-Resistant Staphylococcus aureus
BACKGROUND Mupirocin has been used for the treatment of skin infections and eradication of nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA). The increased use of this antibiotic has been accompanied by outbreaks of MRSA that are resistant to mupirocin. OBJECTIVE This study aims to determine the prevalence, genotype and antimicrobial susceptibility of mupirocin-resistant MR...
متن کاملRisk Factors of Nasal Carriage of Methicillin-Resistant Staphylococcus Aureus and its Antibiotic Susceptibility Pattern in Namazi hospital Healthcare Workers in Shiraz, Iran
Background & Aims: Methicillin-resistant Staphylococcus aureus (MRSA) is a major nosocomial pathogen worldwide. The aim of this study was to determine the risk factors of nasal carriage of MRSA and its antibiotic susceptibility pattern among healthcare workers at Namazi Hospital (Shiraz-Iran) Methods: In a cross-sectional study from July to November 2006, nasal swabs were taken from 600 stratif...
متن کاملشناسایی مقاومت به موپیروسین در سویه‌های استافیلوکوکوس اورئوس جدا شده از بیماران 4 بیمارستان دانشگاهی تهران با روش PCR
Introduction: Mupirocin, an inhibitor of bacterial isoleucyl-tRNA synthetase, has used to treat staphylococcal skin infections as well as to eliminate nasal carriage of Staphylococcus aureus. Mupirocin resistant Staphylococcus aureus strains are seen worldwide but there is no report from Iran. In the present study, by using phenotyping methods (disk diffusion and E-test) in combination with P...
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ورودعنوان ژورنال:
- Journal of clinical microbiology
دوره 48 7 شماره
صفحات -
تاریخ انتشار 2010